RESUMO
The morphological study of the development of "intimal thickenings" of the human uterine artery in physiological condition was performed on 72 uterine arteries obtained from foetuses from the 12th week of gestation up to birth. Our results indicate that intimal thickening is formed by the migration and displacement of mesenchymal cells around the site of origin of collateral vessel from uterine mesothelium. These cells firstly differentiate into the myoblasts and then into the myocites. During the development the internal limitans membrane separates the intimal thickening from the tunica media and the elastic fibres appearing inside possessing a muscle-elastic nature. The function of intimal thickenings is the regulation of local blood flow by means of the control of myocitic contractile capacity; these cells play a fundamental role in endothelium-intimal smooth muscle cell contact.
Assuntos
Desenvolvimento Embrionário e Fetal/fisiologia , Túnica Íntima/citologia , Túnica Íntima/fisiologia , Útero/irrigação sanguínea , Artérias/citologia , Artérias/fisiologia , Circulação Colateral/fisiologia , Feminino , Humanos , GravidezRESUMO
The most common cancer arising from an old burn scar is squamous cell carcinoma, while malignant melanoma is rare. There are only four reports in the literature on the combination of the more common tumour with a malignant melanoma and only two cases of malignant fibrous histiocytoma alone. This paper reports the first occurrence of the combination of all three types of cancer in burn scars of the same patient. The factors that promote malignant transformation, such as immunological factors and karyotype, are discussed. We also performed an immunohistochemical study using anti-p53 antibodies.
Assuntos
Queimaduras/complicações , Carcinoma de Células Escamosas/etiologia , Cicatriz/complicações , Histiocitoma Fibroso Benigno/etiologia , Melanoma/etiologia , Neoplasias Primárias Múltiplas/etiologia , Neoplasias Cutâneas/etiologia , Carcinoma de Células Escamosas/patologia , Feminino , Histiocitoma Fibroso Benigno/patologia , Humanos , Melanoma/patologia , Pessoa de Meia-Idade , Neoplasias Primárias Múltiplas/patologia , Neoplasias Cutâneas/patologiaRESUMO
Reconstruction of the tragus is very difficult to perform and most techniques are described for the treatment of microtia where remnants of ear are used. The goal always consists in achieving a prominence that covers the canal. We present a novel and safe method, based on the vascularity of the lobule, that also provides a good appearance.
Assuntos
Carcinoma Basocelular/cirurgia , Neoplasias da Orelha/cirurgia , Orelha Externa/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Retalhos CirúrgicosRESUMO
Many of the techniques available for earlobe reconstruction require that the rest of the ear is in continuity with retroauricular skin and they usually need two stages; in some cases a graft is also required. We present a method to create an earlobe in one stage and without grafts, illustrated by one case report. The technique is a combination of the flap techniques of Davis and Zenteno Alanis, using an extended retroauricular flap together with an anterior ear flap.
